Veterinary
  Antibiotics
-- Flumequine
-- Tilmicosin
-- Tilmicosin Phosphate
-- Florfenicol
-- Tiamulin Fumarate
-- Erythromycin Thiocyanate
-- Ceftiofur Hydrochloride
-- Ceftiofur Sodium
-- Trimethoprim
-- Trimethoprim Lactate
  Antiparasitics
-- Clopidol
-- Diclazuril
-- Niclosamide
-- Niclosamide Piperazine salt
-- Avemectin
-- Ivemectin
-- Fenbendazole
-- Maduramycin
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Veterinary
Tilmicosin
 
Technical Data Sheet
Chemical name:  20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin
Moleculor Formula : C46H80N2O13
Molecular Weight:: 869.15
CAS#: 108050-54-0
Molecular Structure:  
Specifications:
Items
Specifications
Analysis Results
Appearance
White or off white powder
Conform
Identification
1.      This product map of the infrared light absorption of the map should be consistent with the reference substance
2.      Determination under the record of the chromatogram for the sample peak with the retention time of Tilmicosin reference substance consistent peak of retention time
Conform      
Moisture Content
5%
2.0%
Individual Impurities
3.0%
0.9%
Total Impurties
10%
7.3%
Cis- isomer
82.0% ~ 88.0%       
85.7%
Trans- isomer
12.0% ~ 18.0%
14.3%%
Assay (C46H80N2O13)
85.0%
88.9%
Conclusion
All the test results conform to USP30
 
Properties:  White to off-white powder; odorless
Solubility : very slightly soluble,  slightly soluble in n-hexane
 
Melting Range: 107 - 112 C
 
Applications:
Chemical Family: Macrolide antibiotic
Therapeutic Category: Antibacterial (veterinary)
Composition: Pure Material
 
Storage: Keep in lightproof,airproof and dry place
Packing:  In 25kg drums with plastic inner.
 
Mutagenicity Data: Tilmicosin tested negative for reverse mutation in bacteria, forward mutation in cultured animal cells, unscheduled
DNA synthesis in primary cultures of rat hepatocytes, and in in-vivo cytogenic assays.
Reproductive and Developmental Effects: Tilmicosin did not affect fertility or reproduction in rats administered up to 200
mg/kg/day. Growth and development were not affected in the fetuses of pregnant rats
administered up to 500 mg/kg/day by gavage, but there was a slight increase in pup
mortality in the litters of rats given 200 mg/kg/day.
Ecological Information: Practically non-toxic to fish, birds, earthworms, fungus, moulds, soil bacteria, and most plants. Slightly toxic to aquatic invertebrates. Moderately toxic to nitrogen-fixing bacteria. Highly toxic to green algae and blue-green algae. No volatility expected. Low potential to bioconcentrate in aquatic organisms. Low mobility in soil. Persistent in the soil environment. Persistence in the aquatic environment not expected due to rapid photolysis.
 
 
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